Gestational diabetes mellitus and hypothyroidism: two sides of the same coin

نویسندگان

چکیده

Aim . To perform a systematic review of common risk factors and prognostic markers gestational diabetes mellitus (GDM) hypothyroidism (HT), as well maternal perinatal complications in these diseases. For achieving this task, we screened analysed the relevant data from publications PubMed database over past 6 years. Key Points A factor for both diseases is obesity, which characterized by pregestational insulin resistance, combination low-grade chronic inflammation metabolic dysfunction termed meta-inflammation. Antibodies to thyroid-stimulating hormone receptor (TSHR) are associated with reduced GDM. Studies on pathogenesis pre-eclampsia patients GDM HT have shown unequivocal results, although most them suggest development pregnancy complication. Elevated levels antioxidant capacity long-term endothelial activation. The heterogeneity anemia requires rigorous differential diagnosis. Conclusion endocrine during significantly increase complications. Common factors, interrelationship, ambiguous mechanisms indicate need screening detailed monitoring thyroid early detection correction hyperglycemia.

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ژورنال

عنوان ژورنال: ??????????????? ? ??????????? ????????

سال: 2023

ISSN: ['2542-0941', '2500-0764']

DOI: https://doi.org/10.23946/2500-0764-2023-8-2-120-128